Jason Kenji Higa, MS, PhD

Jason Kenji Higa, MS, PhD

Assistant Professor 
Pre-Clerkship Course Director

Jason Higa Profile



  • Affiliation:
    Department of Anatomy, Biochemistry and Physiology
    Office of Medical Education

  • Email: jkenjih@hawaii.edu

  • Phone: (808)692-1009

Short Bio

Jason Kenji Higa, Ph.D., is from the ʻEwa side of Oʻahu and earned his Bachelor's at UH Mānoa, his Master's at the Univ. of San Francisco, and his Ph.D. in Cell & Molecular Biology at UH Mānoa. His postdoctoral studies were in cardiac cell physiology and ferroptosis. He has taught undergraduate Human Anatomy & Physiology since 2016, and was awarded the Frances Davis Award for Excellence in Undergraduate Teaching in 2020.

Dr. Higa also has a dual appointment with the Office of Medical Education at JABSOM, and is a pre-clerkship Course Director and subject lead for physiology for the medical student curriculum. He enjoys traveling and learning new languages. He also loves animals and can be seen bird-watching at both Mānoa and Kakaʻako campuses.

Research Interests

Endocrine & cardiovascular physiology; medical education; natural products; artificial intelligence & machine learning

Selected Publications

Higa, J.K., Kawasaki, N.K., Matsui, T. (2023). Ferroptosis in Cardiovascular Disease. In: Tang, D. (eds) Ferroptosis in Health and Disease. Springer, Cham. https://doi.org/10.1007/978-3-031-39171-2_8

Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes
Yuichi Baba, Jason K. Higa, Briana K. Shimada, Kate M. Horiuchi, Tomohiro Suhara, Motoi Kobayashi, Jonathan D. Woo, Hiroko Aoyagi, Karra S. Marh, Hiroaki Kitaoka, and Takashi Matsui
American Journal of Physiology-Heart and Circulatory Physiology 2018 314:3, H659-H668

Cardiac mTOR rescues the detrimental effects of diet-induced obesity in the heart after ischemia-reperfusion
Toshinori Aoyagi, Jason K. Higa, Hiroko Aoyagi, Naaiko Yorichika, Briana K. Shimada, and Takashi Matsui
American Journal of Physiology-Heart and Circulatory Physiology 2015 308:12, H1530-H1539